>From bettym19@mindspring.comSat Dec 23 18:41:11 1995 Date: Sat, 23 Dec 1995 15:07:22 -0500 From: Betty Martini Newsgroups: misc.health.diabetes Subject: Aspartame/Diabetes/References Dear James: This continues the last post so it won't be so long. Here are some of the references and citations from an article about independent testing on aspartame by Barbara Mullarkey, the journalist who has been writing about aspartame since its approve. The article was titled NEUROTOXIC POTENTIAL OF ASPARTAME. At a later date we will probably scan it in. 1. Stegink, L.: Filer, L.J. Jr. Aspartame Physiology and Biochemistry. University of Iowa College of Medicine. Iowa City, IA Marcel Dekker, Inc. 1984. 2. Camfield, P.R.: Camfield, J.M.: Dooley, J.M.: et al with generalized absence epilepsy: A double-blind controlled study. Neurology (42) 1000-1003 (May 1992) 3. Boehm, M.: Bada, J. Racemization of aspartic acid and phenylalanine in the sweetener aspartame at 100 degrees C. Proc. Natl. Acad. Sci. USA (81) August 1984. 4. Walton, R. G. "Seizure and mania after high intake of aspartame." Psychopathology 17:98-106 (1984) 5. Drake, M.E. "Panic Attacks and Excessive Aspartame Ingestion." The Lancet (Sept 13, l986) p. 631 6. Walton, R. G. "The Possible Role of Aspartame in Seizure Induction" Proceedings of the First International Meeting on Dietary Phenylalanine and Brain Function. (May 8-10 1987) pp.495-499 7. Epstein, C. M.: Trotter, J.F.: et al "EEG Mean Frequencies are Sensitive indices of Phenylalanine Effects on Normal Brain." Electroencephalography and Clinical Neurophysiology 72:133-139 (1989) 8. Pinto, J.M.B." Maher, T. J. "Administration of Aspartame Potentiates Pentlyeneterazole and Fluorothyl-Induced Seizure in Mice." Neuropharmacology 27 (1):51-55 (l988) 9. Olney, John "Excitatory Neurotoxins as Food Additives: An Evaluation of Risk." Neurotoxicology 2:163-192 (1980) 10. Koehler S.M.: Glaros, A. "The effect of aspartame on migraine headache." Headache 28:000-000 (l988) 11. Edmeada, J. Editorial: "Aspartame and Headache." Headache, pp.64-65 (February, 1988) 12. Lipton, R. B.; Newman, L. C.: Solomon, S. "Aspartame and headache, (re:Schiffman et al study)," New England Journal of Medicine 318 (18): 1200-1201 (May 5, 1988) 13. Steinmetzer, R.V.: Kunkel, R.S. "Aspartame and Headache" New England Journal of Medicine 318 (18): 1201 (May 5, 1988) 14. Koehler, Shirley; and Glaros, Alan. "The Effect of Aspartame on Migraine Headache." Headache 28 (1):10-14 (l988) 15. Olney, J. W.; and Ho, Ol. "Brain damage in Infant Mice Following Oral Intake of Glutamate, Aspartate or Cysteine." Nature 227:609-611 (August 8, 1970) 16. Olney, J. W. "Excitotoxic Food Additives - Relevance of Animal Studies to Human Safety." Neurological Behavioral Toxicology and Teratology 6:455-462 (l984). 17. Olney, J. W.; Labruyere, J: DeGubaret, T. "Brain Damage in Mice from Voluntary Ingestion of Glutamate and Aspartame." Neurobehavioral Toxicology 2:125-129 (l980) 18. Roberts, H. J. "Does Aspartame Cause Human Brain cancer?" Journal of Advances in Medicine 4 (4): 231-241 (Winter, 1991). 19. Potenza, D." El-Mailakh, Rif S. "Aspartame: Clinical Update." Connecticut Medical Journal 53 (7): 395-400 (l989) 20. Sardesai, V.M.: Holliday, J.F.; et al. "Effect of Aspartame in Normal and Diabetic Rats." Biochemical Archives 2:237-243 (l986) 21. Federal Register 48:54993-54995 (Dec 8, l983) 22. Yokigoshi, H.: Roberts, C. F>: Caballero, B.: Wurtman, R. J. "Effects of Aspartame and Glucose Administration on Brain and Plasma Levels of Large Neutral Amino Acids and Brain 5-Hydroxyindoles." American Journal of Clinical Nutrition. 40:1-7 (July 1, 1984) 23. Krause, W.:Halminksi, M." et al. "Biochemical and Neuropsychological Effects of Elevated Plasma Phenylalanine in Patients with Treated Phenylketonuria." Journal of Clinical Investigation 75: 40-48 (January, 1985). 24. Pardridge, W.M. "Potential Effects of the Dipeptide Sweetener Aspartame on the Brain. Nutrition and the Brain 7:199-241 (l986) 25. Gaines, S. M.: Bada, J.I. "Reversed Phase, High-Performance Liquid Chromatographic Separation of Aspartame Diastereomeric Decomposition Products." Journal of Chromatography. 389-:219-225 (l987) 26. Filer, L. J.; Stegnink. L.D. "Effect of Aspartame on Plasma Phenylalanine Concentration in Humans." Proceedings of the First International Meeting on Dietary Phenylalanine and the Brain Function (May 8-10, l987) pp 25-26 27. Matalon, R.: Michals, K.:et al. "Aspartame Consumption in Normal Individuals and Carriers for Phenylketonuria (PKU)." Proceedings of the First International Meeting on Dietary Phenylalanine and Brain Function (May 8-10, l987) pp. 81-93 28. Matalon, R. Michals, K." Sullivan, D.; et al. "Aspartame Consumption in Normal Individuals and Carriers for Phenylketonuria (PKU)." University of Illinois at Chicago, Department of Pediatrics, Nutrition and Medical Dietetics and Epidemiology and Biometry, Chicago, Illinois (l986). 29. Tocci, P.M.: Beber, B. "Anomalous Phenylalanine Loading Responses in Relation to Cleft Lip and Cleft Palate." Pediatrics 52: 109-113 (July l973) 30. Steilman, S.D.:Garfinkel, L. "Artificial Sweetener and One Year Weight Change Among Women." Preventative Medicine 15:195-202 (l986) Because this post is getting long more references will be continued on another post. Regards, Betty Mission Possible International 9270 State Bridge Road Suite 215 Duluth, Georgia 30097 Email: bettym19@mindspring.com